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常凌乾老师课题组

组内教师 - 董再再

教育及工作经历

工作经历

2022.07-现今助理教授北京航空航天大学   医学科学与工程学院
2019.09 - 2022.06博士后北京航空航天大学 生物与医学工程学院


教育背景

2014.09-2019.06

硕博连读

中国科学院化学研究所 分子纳米结构与纳米技术重点实验室

导师:方晓红研究员(国家杰青、973项目首席科学家)

2010.09 - 2014.06学士湘潭大学 化学学院


Published Articles

1. Zaizai Dong#,Shi Yan#, Bing Liu, Yongcun Hao, Long Lin, Tianrui Chang, Hong Sun,Yusen Wang, Hu Li, Han Wu, Xinxin Hang, Shiqi He, Jiaming Hu, Xinying Xue*, NanWu*, Lingqian Chang*. Single Living Cell Analysis Nanoplatform forHigh-Throughput Interrogation of Gene Mutation and Cellular Behavior. NanoLetters. 2021, 21(11): 4878-4886.




2. Zaizai Dong, ChuanhaoTang, Libo Zhao, Jiachao Xu, Yayun Wu, Xiaojun Tang, Wei Zhou, Rongxiang He,Rong Zhao, Li Xu, Zhen Zhang, Xiaohong Fang*. A Microwell-Assisted MultiaptamerImmunomagnetic Platform for Capture and Genetic Analysis of Circulating TumorCells. Advanced Healthcare Materials. 2018, 7(24): 1801231.




3. Zaizai Dong#,Yanli Jiao#, Bingteng Xie, Yongcun Hao, Pan Wang, Yuanyuan Liu,Junfeng Shi, Chandani Chitrakar, Stephen Black, Yu-Chieh Wang, L. James Lee, MoLi*, Yubo Fan, Lingqian Chang*. On-chip Multiplexed Single-cell Patterning andControllable Intracellular Delivery. Microsystems & Nanoengineering. 2020,6: 2.




4. Zaizai Dong#,Xinying Xue#, Hailun Liang*, Jingjiao Guan*, Lingqian Chang*. DNANanomachines for Identifying Cancer Biomarkers in Body Fluids and Cells.Analytical Chemistry. 2021, 93(4): 1855-1865.




5. Zaizai Dong#,Yu Wang#, Dedong Yin, Xinxin Hang, Lei Pu, Jianfu Zhang, Jia Geng*,Lingqian Chang*. Advanced Techniques for Gene Heterogeneity Research:Single-cell Sequencing and On-chip Gene Analysis Systems. VIEW. 2022, 3: 20210011.




6. Zaizai Dong#,Chuanhao Tang#, Zhen Zhang, Wei Zhou, Rong Zhao, Lina Wang, JiachaoXu, Yayun Wu, Jiang Wu, Xing Zhang, Li Xu, Libo Zhao*, Xiaohong Fang*.Simultaneous Detection of Exosomal Membrane Protein and RNA by Highly SensitiveAptamer Assisted Multiplex-PCR. ACS Applied Bio Materials. 2020, 3(5):2560-2567.




7. Zaizai Dong, LingqianChang*. Recent Electroporation-based Systems for Intracellular MoleculeDelivery. Nanotechnology and Precision Engineering. 2021, 4: 045001.




8. Xinxin Hang#, Shiqi He#,Zaizai Dong#, Yun Li, Zheng Huang, Yanruo Zhang, HongSun, Long Lin, Hu Li, Yang Wang, Bing Liu, Nan Wu, Tianling Ren, Yubo Fan,Jizhong Lou, Ruiguo Yang, Lan Jiang*, Lingqian Chang*. High-throughput DNATensioner Platform for Interrogating Mechanical Heterogeneity of Single LivingCell. Small. 2022, 2106196.




9. Hong Sun#, Zaizai Dong#,*, Yusen Wang, Dedong Yin, Yang Wang, Lingqian Chang*. Companion-Probe& Race Platform for Interrogating Nuclear Proteins and Migration of LivingCells. Biosensors and Bioelectronics. 2022, 210, 114281.




10. Yang Wang#, Huiren Xu#,Zaizai Dong#, Zhiying Wang, Zhugen Yang, Xinge Yu,Lingqian Chang*. Micro/Nano Biomedical Devices for Point-of-Care Diagnosis ofInfectious Respiratory Diseases. Medicine in Novel Technology and Devices. 2022,14, 100116.




11. Long Lin, Yuqiong Wang, Minkun Cai,Xinran Jiang, Yongyan Hu, Zaizai Dong, Dedong Yin, Yilin Liu,Shaohua Yang, Zhiguang Liu, Jian Zhuang*, Ye Xu, Chuanfei Guo*, LingqianChang*. Multi-microchannel Microneedle Microporation Platform for EnhancedIntracellular Drug Delivery. Advanced Functional Materials. 2021, 2109187.




12. Yan Sheng#, Zena Huang#,Tenghua Zhang#, Feiyang Qian, Yuqing Zhu, Zaizai Dong,Qingyang Zhang, Qi Lei, Fanhui Kong, Yuqiong Wang, Maddie Walden, StefanWuttke, Lingqian Chang*, Wei Zhu*, Jiaming Hu*. Living Cell Nanoporation andExosomal RNA Analysis Platform for Real-Time Assessment of Cellular Therapies. Journalof the American Chemical Society. 2022.




13. Yang Wang, Hong Sun, Qingyang Zhang,Gaolian Xu, Zhiying Wang, Zaizai Dong, Wenhui Chen, XiaoxiaoYang, Anbang Qiao, Yubo Fan, Xinxia Cai, Lingqian Chang, Bo Wei. A MultiplexedElectrochemical Quantitative Polymerase Chain Reaction Platform for Single-baseMutation Analysis. Biosensors and Bioelectronics.




14. Wei Zhou, Guogui Sun, Zhen Zhang, LiboZhao, Li Xu, Hongyu Yuan, Shumu Li, Zaizai Dong, Yongmei Song*,Xiaohong Fang*. Proteasome-Independent Protein Knockdown by Small-MoleculeInhibitor for the Undruggable Lung Adenocarcinoma. Journal of the AmericanChemical Society. 2019, 141(46): 18492-18499.




15. Xiao-Jun Tang, Yayun Wu, Rong Zhao,Xiaolong Kou, Zaizai Dong, Wei Zhou, Zhen Zhang, Weihong Tan, andXiaohong Fang*. Photorelease of Pyridines Using a Metal-Free PhotoremovableProtecting Group. Angewandte Chemie-International Edition. 2020, 59(42).18386-18389.




16. Xinxin Hang, Shiqi He, ZaizaiDong, Grayson Minnick, Jordan Rosenbohm, Zhou Chen*, Ruiguo Yang*,Lingqian Chang*. Nanosensors for Single Cell Mechanical Interrogation. Biosensors & Bioelectronics. 2021, 179: 113086.




17. Yang Wang, Kaiju Li, Gaolian Xu, ChuanChen, Guiqin Song, Zaizai Dong, Long Lin, Yu Wang, Zhiyong Xu,Mingxia Yu, Xinge Yu, Binwu Ying*, Yubo Fan*, Lingqian Chang*, Jia Geng*.Low-Cost and Scalable Platform with Multiplexed Microwell Array Biochip forRapid Diagnosis of COVID-19. Research. 2021, 2813643.




18. Yayun Wu, Hefei Ruan, Rong Zhao, ZaizaiDong, Wenhui Li, Xiaojun Tang, Jinghe Yuan, Xiaohong Fang*. UltrastableFluorescent Polymer Dots for Stimulated Emission Depletion Bioimaging. AdvancedOptical Materials. 2018, 6(19): 1800333.




19. Zhen Zhang*, Chuanhao Tang, Libo Zhao,Li Xu, Wei Zhou, Zaizai Dong, Yuqing Yang, Qiqi Xie, XiaohongFang*. Aptamer-Based Fluorescence Polarization Assay for Separation-FreeExosome Quantification. Nanoscale. 2019, 11(20): 10106-10113.




20. Ping-An Chen, Jin Guo, Mehdi Nouri,Quanyang Tao, Zhiwei Li, Qianyuan Li, Lulu Du, Huajie Chen, Zaizai Dong,Lingqian Chang*, Yuan Liu, Lei Liao, Yuanyuan Hu*. MicrofluidicSolution-processed Organic and Perovskite Nanowires Fabricated for Field-effectTransistors and Photodetectors. Journal of Materials Chemistry C. 2020, 8(7):2353-2362.




21. Yayun Wu, Hefei Ruan, ZaizaiDong, Rong Zhao, Jianqiang Yu, Xiaojun Tang, Xiaolong Kou, Xing Zhang,Manchen Wu, Fang Luo, Jinghe Yuan*, Xiaohong Fang*. Fluorescent PolymerDot-Based Multicolor Stimulated Emission Depletion Nanoscopy with a SingleLaser Beam Pair for Cellular Tracking. Analytical Chemistry. 2020, 92(17),12088-12096.




22. Qianmin Zhang#, XiaojuanWei#, Yongli Ji#, Li Yin, Zaizai Dong, FengChen*, Mingqiang Zhong, Jian Shen, Zhenjie Liu*, Lingqian Chang*. Adjustableand Ultrafast Light-cured Hyaluronic Acid Hydrogel: Promoting Biocompatibilityand Cell Growth. Journal of Materials Chemistry B. 2020, 8(25): 5441-5450.


Book Chapter

Zaizai Dong#, Tongren Yang#,Han Wu, Justin Brooks, Ruiguo Yang, Yuanyu Huang, Lingqian Chang. Chapter 5: Advancedmicrofluidic devices for cell electroporation and manipulation. MICRO AND NANOSYSTEMS FOR BIOPHYSICAL STUDIES OF CELLS AND SMALL ORGANISMS. Elsevier. 2021.


Patent

1. 常凌乾;董再再,基于单细胞阵列的纳米电穿孔装置及其应用,CN112226365A

2. 常凌乾;董再再; 孙宏,一种新型活细胞核内蛋白检测方法与装置,202210384917.0

3. 常凌乾;董再再; 万凤奇,一种活细胞内增强子活性鉴定方法与装置,202210492754.8

4. 方晓红;董再再;赵立波;张振;周卫;徐丽,一种基于核酸适体免疫PCR共同表征外泌体膜标志物和RNA的方法,ZL201911011894.3

5. 方晓红;董再再;赵立波;张振;徐丽;周卫,一种耐药异质性循环肿瘤细胞捕获与基因分析的试剂、装置和方法,ZL201811180288.X

6. 方晓红;张振;董再再;徐丽,核酸适体酶联检测试剂盒和制备方法及其应用,ZL201810677985.X

7. 方晓红;张振;赵子龙;徐丽;董再再;赵立波,一种亲和丙型病毒性肝炎核心蛋白的核酸适体及其应用,ZL201410219472.6

8. 方晓红;张振;赵子龙;徐丽;董再再;赵立波,亲和丙型病毒性肝炎核心抗原的核酸适体及其应用,ZL201410482700.9